Resistance to anti-estrogen therapy in breast cancer due to natural cell...
Most breast cancers are fueled by estrogen, and anti-estrogenic agents often work for a time to control the cancers. But many of these cancers become resistant to the drugs for reasons that are not...
View ArticleQuicker detection and treatment of severe sepsis
Sepsis is the name of an infection that causes a series of reactions in the body, which in the worst case can prove fatal. The problem for both patients and doctors is that the early symptoms are...
View ArticleRett protein MeCP2 needed for proper adult neuron function
The protein MeCP2 is porridge to the finicky neuron. Like Goldilocks, the neuron or brain cell needs the protein in just the right amount. Girls born with dysfunctional MeCP2 (methyl-CpG-binding...
View ArticleDevelopmental disease is recreated in an adult model
A new study published today in the journal Science has shown that the childhood disorder Rett syndrome, can be reestablished in adult animals by "switching off" a critical disease causing gene in...
View ArticleSugar-binding protein may play a role in HIV infection
Specific types of "helper" T cells that are crucial to maintaining functioning immune systems contain an enzyme called PDI (protein disulfide isomerase).
View ArticleTranscription factor regulates protein that dampens immune responses
Interleukin-10 (IL-10) is an anti-inflammatory cytokine protein that reduces immune responses and staves off autoimmune disease. Now, a research team led by Masato Kubo at the RIKEN Research Center for...
View ArticleScientists find new drug candidates for set of protein-folding diseases
Collaborating researchers at Stanford University and The Scripps Research Institute have identified chemical compounds that show promise as potential therapeutics for a set of medical conditions caused...
View ArticleScientists identify key protein linked to acute liver failure
New research from the Keck School of Medicine of the University of Southern California (USC) may help prevent damage to the liver caused by drugs like acetaminophen and other stressors.
View ArticlePossible new blood test to diagnose heart attacks
Loyola University Chicago Stritch School of Medicine researchers are reporting a possible new blood test to help diagnose heart attacks.
View ArticleProgression of lung fibrosis blocked in mouse model
A study by researchers at the University of California, San Diego School of Medicine may lead to a way to prevent the progression, or induce the regression, of lung injury that results from use of the...
View ArticleMaking memories last: Prion-like protein plays key role in storing long-term...
Memories in our brains are maintained by connections between neurons called "synapses". But how do these synapses stay strong and keep memories alive for decades? Neuroscientists at the Stowers...
View ArticleCurry spice component may help slow prostate tumor growth
Curcumin, an active component of the Indian curry spice turmeric, may help slow down tumor growth in castration-resistant prostate cancer patients on androgen deprivation therapy (ADT), a study from...
View ArticleBone marrow transplant arrests symptoms in model of Rett syndrome
A paper published online today in Nature describes the results of using bone marrow transplant (BMT) to replace faulty immune system cells in models of Rett Syndrome. The procedure arrested many severe...
View ArticleDengue virus turns on mosquito genes that make them hungrier
Researchers at the Johns Hopkins Bloomberg School of Public Health have, for the first time, shown that infection with dengue virus turns on mosquito genes that makes them hungrier and better feeders,...
View ArticleProtein heals wounds, boosts immunity and protects from cancer
Hans Vogel, a professor in the biological sciences department, is the guest editor of a special issue of the journal Biochemistry and Cell Biology that focuses on lactoferrin, an important iron-binding...
View ArticleScientists explain how they created bird flu that spreads easily among mammals
Scientists have created versions of the H5N1 bird flu that spread easily among mammals through droplets in sneezes and have concluded that the deadly virus could trigger a global pandemic in humans.
View ArticleA drug-screening platform for ALS
A research group at the Center for iPS Cell Research and Application (CiRA) at Japan's Kyoto University has successfully recapitulated amyotrophic lateral sclerosis (ALS)-associated abnormalities in...
View ArticleBinding sites for LIN28 protein found in thousands of human genes
A study led by researchers at the UC San Diego Stem Cell Research program and funded by the California Institute for Regenerative Medicine (CIRM) looks at an important RNA binding protein called LIN28,...
View ArticleCell death mystery yields new suspect for cancer drug development
A mysterious form of cell death, coded in proteins and enzymes, led to a discovery by UNC researchers uncovering a prime suspect for new cancer drug development.
View ArticleSugar-free approach to treating Kaposi sarcoma
A sugar-loving protein drives the growth of Kaposi sarcoma (KS) tumors, according to a study published on October 1st in The Journal of Experimental Medicine. Interfering with these sugary interactions...
View Article
